Last update: 09.07.2011
Researchers counteract biofuel toxicity in microbes
Source : rdmag.com
Advanced biofuels are highly touted as potential replacements for gasoline, diesel, and jet fuels. Equally touted is the synthesis of these fuels through the use of microbes. However, many of the best candidate compounds for advanced biofuels are toxic to microbes, presenting a "production versus survival" conundrum. Researchers at the U.S. Department of Energy (DOE)'s Joint BioEnergy Institute (JBEI) have provided a solution to this problem by developing a library of microbial efflux pumps that were shown to significantly reduce the toxicity of seven representative biofuels in engineered strains of Escherichia coli. "Working with all available microbial genome sequence data, we generated a library of largely uncharacterized genes and were able to devise a simple but highly effective strategy to identify efflux pumps that could alleviate biofuel toxicity in E. coli and, as a consequence, help improve biofuel production", says Aindrila Mukhopadhyay, a chemist with JBEI's Fuels Synthesis Division, who led this research.
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16 May 2011 |
United States & Canada
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Articles in the category 'Research' (133 articles)
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